How Do Hemp-Based CBD Products Interact With the Brain

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Hemp-based CBD manufacturers are often asked how their products interact with cbd and the brain.

The brain is like the captain of a deep-sea ship. In a constant struggle to keep the ship level as Himalayan-sized waves come crashing down.

This process is called homeostasis. Both the brain and endocannabinoid systems act as dams and reservoirs for all our hormones and neurotransmitters.

CBD is like finding a secret map with pathways unknown to the crew beforehand. It unlocks new ways for the endocannabinoid system to function.

When It Comes to CBD and the Brain 

Endocannabinoid anandamide can build up when receptors aren’t running at full speed. This is why CBD and the immune system are of special interest to hemp manufacturers.

While CBD may stop these receptors from accepting as much anandamide, there needs to be further research to see if this method can help with issues like anxiety.

This article explains the basics of how CBD interacts with the nervous system on a purely physical level. There are many promising studies on CBD, but nothing is confirmed yet.

Always consult a physician before adding CBD to your routine.

The Bliss Molecule

The most common enzymes in the endocannabinoid system are fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). Studies have found about 20% of people have a FAAH deficiency.

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This means they aren’t breaking down anandamide, often referred to as the “bliss molecule”.

Without breaking down this bliss molecule, it builds up in the body. People with this defect tend to be less anxious than those with more active FAAH production.

Unlike AG-2 which is a welcome guest in either receptor, Anandamide only heads towards CB1 in the central nervous system.

Anandamide’s power over the CB1 receptors is equally strong as THC but without any psychoactive properties.

How It Got Its Name

In the style of ancient tongue Sanskrit, “ananda” translates to “bliss”. It was first discovered by the same man who discovered THC in marijuana.

Renowned chemist Dr. Raphael Mechoulam wanted to understand why our bodies’ endocannabinoid receptors have the potential to pair with external cannabinoids.

When it comes to anandamide, our bodies only bother to make it as needed. As soon as it’s made, anandamide is like a smartphone screen–quick to break down.

Meaning it doesn’t stick around for long. Because anandamide is involved with so many biological processes, changing the flow can result in changes to mood, appetite, and inflammatory responses.

Always in pursuit of homeostasis, our body shoots out anandamide to encourage the development of fresh nerve cells in the brain.

Studies with mice have show anandamide’s aptitude for quelling anxiety when there is an immediate threat nearby. Other researchers found anandamide to be vital for ovulation and fetal development.


One of the main endocannabinoids made by the body is 2-Arachidonoylglycerol (2-AG). To finish its journey, 2-AG goes through a very complex-sounding process called retrograde signaling.

Most neurotransmitters travel from a presynaptic neuron, through a synapse, and out to a postsynaptic neuron.

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This is how your brain commands your body to do everything from downing your bowl of cereal in the morning to lifting your legs for your after-work jog.

2-AG is like that hyper kid running the wrong way up the escalator. By turning the mechanism upside down, 2-AG works itself from the postsynaptic neuron backward to the presynaptic neuron.

 By doing this 2-AG is able to regulate the immune system’s inflammatory responses. When you hit a rock and fall off your bike, 2-AG is on the scene making sure the inflammation and healing processes begin immediately.

Mood, bone health, and reproduction among other bodily processes are all in some way affected by 2-AG’s presence.

Alzheimer’s And CBD

While more research is needed, why was it theorized CBD could help with degenerative diseases in the first place?

It all has to do with the mechanisms that control the body’s decline. Alzheimer’s causes brain cells to waste away without any way of replacing them.

When researchers look at how CBD reacts in the body, it’s not unlike the way society implements quarantine restrictions to prevent diseases from spreading.

Alzheimer’s is like a hyper dog tearing up all of its chew toys. It ravages the brain and leaves the mess for someone else.

CBD acts as a speakerphone telling the immune system to chill out. Medical researchers are hopeful that this unique aspect of CBD may be able to stave off the massive cell death degenerative diseases cause.

Another interesting aspect of Alzheimer’s is increased oxygen in the brain. Sounds like a good thing, right?

But this oxygen is released as a byproduct of the disease killing off healthy cells. As oxygen levels increase in the brain because of this, memory and cognition are generously slowed.

So what is the solution to too much oxygen? Antioxidants!

CBD is known for its antioxidant properties leading to the hypothesis it may help deter some of this damage. CBD

Vascular Dementia

Vascular dementia happens when not enough blood is making its way to the brain.

Researchers found that stimulating CB2 endocannabinoid receptors can send much-needed blood to a vascular dementia-affected brain.

Could CBD help stimulate endocannabinoid receptors to help slow degenerative disorders?

More research is needed but is promising for those suffering from these conditions.

Dravet Syndrome and the Tug of War on CBD

Because there is only one FDA-approved CBD product, one question remains on US-based hemp manufacturer’s minds across the county.

If CBD pill Epidolex is classified as a drug, what does that make brands and retailers selling other sources of the cannabinoid?

A key difference between Epidolex and what hemp-based product manufacturers, like Spring Creek Labs, are making is the source.

Epidiolex uses marijuana-extracted CBD instead of sourcing from hemp. Developed to help alieve some of the seizures associated with Dravet Syndrome, doctors are still stumped as to why Epidolex helps.

This makes it all that much harder for private label CBD manufacturers to nail down the benefits of CBD.

It’s also important to note that Epidolex is a highly processed pharmaceutical with a process CBD manufacturers can’t recreate. Do not use CBD supplements as a treatment for any medical condition.

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So if the world’s top researchers and physicians studying CBD don’t know all the details of how it works, how can brands provide top-notch products their customers’ trust?

Start With the Freshest U.S. Grown Hemp

Spring Creek Labs is the hemp-based CBD product manufacturer able to deliver high-quality CBD products even during a pandemic. How does it work?

With so many startups outsourcing these days, Spring Creek Labs started building its supply chain in-house from the beginning.

Because they own their hemp farms and processing facilities, Spring Creek labs doesn’t leave its customers vulnerable to harmful additives like many other US-based CBD manufacturers.

It’s why so many brands turn to them for their private label CBD products. A private label hemp manufacturer, like Spring Creek Labs, gives startups access to hundreds of thousands of dollars of equipment and labor without a huge investment.

Partner with a CBD nootropics manufacturer who won’t leave your customers scrounging for their favorite products. Call now and see how easy it is to ramp up production on your own line of CBD oils and products today!